The issues appears to be related to the ability to execute comskip.exe
ERROR> 2021-08-26T22:14:42 MCEBuddy.AppWrapper.Comskip --> Application File Not Found or not accessible : C:\Program Files\MCEBuddy2x\comskip\comskip.exe
ERROR> 2021-08-26T22:14:42 MCEBuddy.CommercialScan.Scanner --> Comskip failed
ERROR> 2021-08-26T22:14:42 MCEBuddy.Engine.ConversionJob --> Advertisement scan failed
Check C:\Program Files\MCEBuddy2x\comskip\ and make sure comskip.exe is in there. If it is then I’m not sure why it can’t run it, if it isn’t then try uninstalling and reinstalling. Check that your antivirus application isn’t quarantining it.